Abstract Background Hepatocellular carcinoma (HCC) is one of the most common and lethal cancers worldwide, but current treatment options remain limited and cause serious life-threatening side effects.Aberrant FGFR4 signaling has been validated as an oncogenic driver of HCC, and EZH2, the In Print catalytic subunit of the PRC2 complex, is a potentia
Abstract In this volume of Artifact, we wish to explore design through the design concept, and thereby the societal praxis of designers through the theoretical concept of design.Design is praxis, but it is also formed by the way we frame the concept of design.We have endeavoured to give space for a rather broad range of contributors coming from bot
Function diversification in large protein families is a major mechanism driving expansion of cellular networks, providing organisms with new metabolic capabilities and thus adding to their evolutionary success.However, our understanding of the evolutionary High Speed Oven Accessories mechanisms of functional diversity in such families is very limit
When implementing projects on motor roads, financial and economic analysis of specific projects are usually provided.This article deals with the mathematical model which enables to analyze the entirety of projects on the motor road network with the view of determining which of them would Bandage Protector give benefit to society the fastest and cou